The Sampson Laboratory

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The overall goal of the Sampson Lab is to help improve the health of children with nephrotic syndrome through applied genomics, with a focus on samples and data collected from patients with this condition. We use computational genomics and bioinformatics to discover new, and map known, nephrotic syndrome-associated variants. We use systems genomics to integrate this genetic data with other genome-scale molecular datasets to try to understand the mechanisms linking these genetic changes with disease. And we use epidemiology to discover the clinical consequences for patients carrying disease-associated genetic variants.